The data showed that 39% of the patients with current HBV infection and 30% of the patients with resolved HBV infection experienced AFs (serum ALT level >2 times ULN) of hepatitis B. Reactivation of HBV (≥2 log increase in HBV DNA compared to the baseline level) was found in only two of the HBsAg-positive patients, and none of the patients with resolved HBV infection. The gene discussed is GPT; the disease is Hepatitis.