Summing up, the consumption of feed with 1% of high-molar-mass oat beta-glucan decreased the gene expression of Ccr2, Ccr5, and Cxcr2 in colitis rats at both time points, while the consumption of feed with low-molar-mass oat beta-glucan decreased the gene expression of Ccr1 and Ccr2 only after 3 days of colitis induction. The gene discussed is CCR5; the disease is colitis.