SPP1 and colitis: Most importantly, the results of the FLD analysis confirmed the results of ANOVA and indicated that after 3 days of the experiment, the gene expression of Ccl3, Ccl4, Cxcl1, Cxcl2, Cxcl9, Ccr1, Ccr2, Ccr5, Cxcr2, Csf3, Osm, and Spp1 was higher in the rats from the colitis βG− group compared to control groups, while after 7 days, only the gene expression of Ccl4, Ccl5, Cxcl1, Cxcl2, Cxcl11, Ccr2, Ccr5, Cxcr2, and Spp1 was higher.