After 3 days of colitis induction, reduced expression of genes such as Ccl3 and Ccl4 and that of chemokine receptors Ccr1 and Ccr2 was observed in colitis animals receiving feed supplemented with low-molar-mass oat beta-glucan, while the animals receiving feed with high-molar-mass beta-glucan showed decreased expression of the chemokines Ccl3, Ccl4, Cxcl1, and Cxcl2 and the receptors Ccr1, Ccr2, Ccr5, and Cxcr2. The gene discussed is CXCL1; the disease is colitis.