TNF and Hyperglycemia: However, 24 h after the stimulation with Hb-Hp1-1 complexes, suppression of TNFα secretion was detected in both normo- and hyperglycemic conditions, with a statistically significant effect in hyperglycemia 24 h after stimulation with 10 μg/mL Hb-Hp1-1 complexes (1.29 times suppression, p-value < 0.05).