SCN5A and Brugada syndrome: However, a large array of SCN5A mutations linked to ventricular fibrillation are reported in the context of additional cardiac impairments, such as Brugada syndrome [410,411,412,413], atrial fibrillation [414], acute myocardial infarction [415,416,417], sudden cardiac death [418,419], or Graves’ disease [420].