CASP3 and cancer: In agreement with this observation, we analyzed the levels of expression of Akt, a protein known to increase the survival of cancer cells [46] and found that it was induced in both types of C57-IKKα cells (Figure 7E), while a lower than control amount of the proapoptotic cleaved-Caspase 3 was detected in both C57-C-IKKα and C57-N-IKKα cells (Figure 7E).