MIR191 and ovarian neoplasm: As can be seen from Figure 1, a highly statistically significant (p < 0.001, FDR = 0.01) increase in the methylation level of 18 out of 20 miRNA genes was observed in OvCa passing from control samples (15 and 83 samples) to primary ovarian tumors (102) and peritoneal macroscopic metastases (30): MIR107, MIR124-1, MIR124-2, MIR124-3, MIR125B-1, MIR1258, MIR127, MIR129-2, MIR130B, MIR132, MIR137, MIR148A, MIR193A, MIR339, MIR34B/C, MIR375, MIR9-1, and MIR9-3, while the MIR191 gene had a highly statistically significant (p < 0.001, FDR = 0.01) decrease in the methylation level.