TP53INP1 and neoplasm: Increased levels of miR-155 have previously been reported in PDAC patients compared with normal pancreatic tissues and have been shown to suppress the pro-apoptotic gene p53 (TP53INP1), which plays a crucial role in p53 function, in inducing growth inhibition and autophagic cell death, in the repression of tumor cell migration, in cell growth arrest and apoptosis [75].