In eight GWAS related to obesity ([42,43] and Supplementary Figure S9 legend), many candidate regulatory SNPs located 11–120 kb upstream of RP11-392O17.1 were associated with LYPLAL1 (Lysophospholipase-like 1) and overlapped the RefSeq gene structure LYPLAL1-AS1/NR_135822.1 (Figure 4H, tan rectangle). This evidence concerns the gene LYPLAL1 and obesity due to melanocortin 4 receptor deficiency.