EEF2 and infection: For P. aeruginosa it has been shown that infection is followed by subsequent increase of calcium influx [34], which could be due to pore-forming toxins such as exolysin A. However, calcium-imaging experiments revealed an increase of intracellular calcium upon stimulation with ExoA, which functions as ADP-ribosyltransferase inactivating eEF-2 [31].