In the next study, we will conduct further investigation to determine whether BITC suppresses IL-1β -induced fibrosis in nasal-polyp-derived fibroblasts (NPDFs) via the excessive accumulation of cellular sources of extracellular matrix (ECM) proteins, which are hallmarks of fibrosis, such as collagen-1 and fibronectin, that could be involved in the growth of NPs. The gene discussed is PROS1; the disease is nasal cavity polyp.