DBP and posterior cortical atrophy: In a recent in silico study, the DBP protein target was evaluated to investigate the AR–ligand interaction, confirming how such phthalate activates, independently from the receptor AR, the androgen signaling pathways, leading, as confirmed in vitro, to androgen-independent PCa-promoting effects and, in turn, potentially triggering the mechanism relevant for the onset or progression of PCa [137].