The relative risk for breast cancer and ovarian cancer is 5.9 (95% confidence interval (CI): 5.3–6.7) and 11.8 (95% CI: 10.0–14.0) for BRCA1 mutant carriers, respectively, and 3.3 (95% CI: 3.0–3.7) and 5.3 (95% CI: 4.4–6.3) for BRCA2 mutant carriers, respectively [25]. This evidence concerns the gene BRCA2 and breast carcinoma.