It is not clear whether pancreatic cancer susceptibility genes such as BRCA1, BRCA2, CDKN2A, mismatch repair genes (MLH1, MSH2, MSH6, PMS2, and EPCAM), ATM, PALB2, STK11, and TP53 are associated with IPMNs. This evidence concerns the gene BRCA2 and familial pancreatic carcinoma.