A report with two 18F-fluoroglycosylated urea-based PSMA agents, 2-[18F]FGlc-PSMA and 6-[18F]FGlc-PSMA (Figure 4), demonstrated that incorporation of an 18F-labeled glycosyl moiety increases the hydrophilicity thus improving the tumor-to-kidney ratio [79]. This evidence concerns the gene FOLH1 and neoplasm.