In fact, ours and other groups have previously demonstrated that GBM is characterized by the presence of several aberrant splicing variants (e.g., of TP73, GLI1, MAPKs, growth factor receptors, matricellular proteins, etc. [8,42,43]), reinforcing the idea that an aberrant alternative splicing could be also one of the hallmarks of GBM as happens in other cancer types. The gene discussed is TP73; the disease is cancer.