CD4 and tuberculosis: A 6-month therapy, both in drug sensitive (DS)- and drug resistant (DR) TB patients, was found to result in a decreased frequency of conventional T regulatory (cTreg) mTNF+, CD4+mTNFR1+ and CD4+mTNFR2+, however the decreased frequency of activated CD4+ mTNF+ and CD4+ mTNFR2+ was noticed only in DR-TB patients.