FABP1 and Hepatic steatosis: It has been found that T3 blocks the development of liver steatosis by increasing the β-oxidation of fatty acid by mitochondria and peroxidase, and decreasing liver-type fatty acid binding protein expression (l-FABP) in animal models [79], lacking of choline methionine diet (CMD) led to a large number of triglyceride accumulation in the liver and liver injury in mice, which is closely similar to the pathological and biochemical characteristics of human NASH and is used in the study of NASH commonly [80,81].