TGFB1 and infectious otitis media: In turn, an increased level of postsynaptic proteins involved in glutamatergic signalization—NR1 subunit of NMDA receptor and PSD-95—in the brain cortex membrane fraction by ~29% and ~63% for the AOM model and by ~61% and a tendency toward the increase in mice after TGF-β1 neutralization, respectively, was observed (Figure 5A).