MECOM and neoplasm: In corresponding experimental models, EVI1 promoted proliferation, colony formation, anchorage-independent growth, migration, invasion, tumor sphere formation (an in vitro surrogate for cancer stem cell activity), epithelial-to-mesenchymal transition, resistance to drug-induced apoptosis, and/or tumor growth and metastasis formation in syngeneic or xenotransplantation mouse models [8,9,11,12,25,26,27,28,29,30].