COL1A2 and Ehlers-Danlos syndrome, arthrochalasia type: AEDS is caused by heterozygous mutations resulting in partial or complete loss of exon 6 of the COL1A1 (17q21.33) or COL1A2 (7q21.3) genes causing bilateral congenital hip dislocation, generalized joint hypermobility, and hyperextensible and/or fragile skin [8].