In addition, Takami et al. reported that CCNDBP1 protein expression in hepatocellular carcinoma (HCC) was associated with pathologic differentiation by demonstrating its expression upon the initiation of hepatocarcinogenesis and a more positive staining in well-differentiated HCC than in poorly differentiated HCC [10]. This evidence concerns the gene CCNDBP1 and hepatocellular carcinoma.