For example, diet supplementation with some particular nutrients such as omega-3 fatty acids, vitamins B1, B3, B6, B12 and D, magnesium, zinc and β-carotene contributes to the alleviating of chronic pain as seen in systematic reviews in different pain populations including aromatase inhibitor-related arthralgia in breast cancer [55]. Here, CYP19A1 is linked to breast carcinoma.