The aim of this study was to identify genetic risk factors for breast hypertrophy among genes for aromatase (CYP19A1) and progesterone receptor (PGR), examining their single nucleotide polymorphisms (SNPs) (CYP19A1: rs749292 and rs7172156 and PGR: rs1042838). The gene discussed is CYP19A1; the disease is Breast hypertrophy.