CYP19A1 and Breast hypertrophy: There were no differences in the minor alleles’ frequency between the groups in rs1042838 PGR (gigantomastia 17.5% vs. controls 14.06% vs. EU population 16.31%) and in rs749292 CYP19A1(gigantomastia 48.33% vs. controls 59.38% vs. EU population 44.12%).