In treated rats, circulating inflammatory cytokines IL-1, IL-2, IL-4, IL-5, IL-6, IL-7, IL-10, IL-12, IL- 13, IL-17, IL-18, TNF-α, GRO/KC, and RANTES and chemokines G-CSF, M-CSF, MCP-1, and MIP-3α were significantly higher in a phase of compensated cirrhosis (T4) than in decompensated cirrhosis (T12). Here, CALCA is linked to Cirrhosis.