The laboratory elements for defining cholangitis were elevated bilirubin in 60.5% (66/109); white blood cells and elevated liver tests in 32.1% (35/109); two laboratory criteria (elevated white blood cells (WBCs) and elevated bilirubin) in 29.3% (32/109), elevated inflammatory parameters (C-reactive protein (CRP) and/or procalcitonin (PCT)) in 16.5% (18/109); positive blood cultures were required to define cholangitis in 13.7% (15/109) of the articles. This evidence concerns the gene CRP and cholangitis.