ANXA5 and central nervous system cancer: Additionally, the in vitro MTT assay results showed its effective anticancer activity against the glioma U118 MG cancer cell line with an IC50 value of 9.77 μg/mL AgNPs by initiating apoptosis as identified by a staining study with flow cytometric Annexin V–Fluorescein Isothiocyanate (FITC) and Propidium Iodide (PI).