A similar result was obtained by a recent study, in which, compared to the control, an increased concentration of NP-Pt (0.14 μM/mL; 0.29 μM/mL; 0.65 μM/mL) resulted in linearly decreased cell vitality at a comparable level to cisplatin treatments in U87 GBM cells due the increased amount of cell death and induction of apoptosis that was detected in the Annexin V/PI assay [62]. The gene discussed is ANXA5; the disease is glioblastoma.