Similarly, methanol fruit extract of S. cumini exhibited significant in vitro (heat-induced hemolysis, albumin denaturation, bovine serum albumin denaturation) and in vivo (carrageenan-induced paw edema, formaldehyde-induced paw edema, PGE2-induced paw edema) anti-inflammatory activities, which were considerably higher than 50% aqueous methanol and dichloromethane extracts [37]. The gene discussed is ALB; the disease is edema.