Finally, the lncRNAs XIST, H19, MEG3, and LINC01291 were shown to confer resistance of melanoma cells to platinum compounds by regulating miR-21/PI3KR1 miR-18/IGF1, miR-499-5p/CYLD, and miR-625-5p/IGF-1R axis, respectively [136,194,195,196]. This evidence concerns the gene H19 and melanoma.