C9orf72 and amyotrophic lateral sclerosis: Analysis of myo-miRNAs found miR-1 downregulated in SOD1-ALS and sALS patients, miR-206 upregulated in the skeletal muscle of C9orf72-ALS and SOD1-ALS patients, miR-133a downregulated in sALS and UMN patients and miR-133b downregulated in sALS patients compared to healthy controls [63].