NPPB and hydrops fetalis: Further, in Cox regression we found that compared with RHC derived mean pulmonary arterial pressure (mPAP), echocardiography derived TAPSE and RV S’, NT-proBNP (HR: 1.12; CI: 1.01–1.28, p = 0.05) and circulating miR-21 (HR: 0.92; CI: 0.84–0.99, p = 0.02) showed a relatively significant impact on hospitalization for HF in the studied patients.