EPO and anemia: Response of anemia to epoetin treatment has been reported in 45–50% of MF patients, mainly in the context of inadequate endogenous erythropoietin level (<125 U/L) and non-transfusion-dependent anemia: female sex, leukocyte count ≥10 × 109/L, and serum ferritin < 200 ng/mL seem to confer a significantly higher probability of response to erythropoiesis-stimulating agents [120,121,122].