TSC22D3 and infection: To assess this, alveolar macrophages (AMJ2-C11) were pre-treated with TAT (1 μg/mL) or TAT-GILZ (2 μg/mL) for 18 h, followed by infection with 2 × 106 CFU of S. pneumoniae for 3 h (Experimental design in Figure 6A), and phagocytosed bacteria by alveolar macrophages were enumerated.