We applied a similar analysis to ccRCC TCGA samples and observed a similar segregation of the tumors into VHLmut and VHLWT groups, and, again, 786-O-Ctrl clustered with VHLmut tumors, whereas 786-O-VHL clustered with VHLWT tumors (Figure 2H). This evidence concerns the gene VHL and nonpapillary renal cell carcinoma.