In addition, IF analysis allowed us to confirm that some of these proteins changed its localization and abundance between poorly metastatic and highly metastatic CRC cells (i.e., AHR from the cytoplasm to the nucleus, PHYHIPL from the cytoplasm to the membrane, or CLDN3 mainly from the cytoplasm to the membrane, especially in the KM12 cell system). This evidence concerns the gene CLDN3 and colorectal carcinoma.