GLG1 and colorectal carcinoma: Importantly, GLG1 plasma levels significantly increased from premalignant individuals to stage IV CRC patients, where the highest difference in GLG1 plasma levels were observed (1822.74 ± 556.89 pg/mL for stage IV CRC patients vs. 412.26 ± 39.82 pg/mL for controls, p-value = 0.00017) (Figure 7B).