The change in seven biomarkers selected by the multivariable model for the persistence of cardiac dysfunction post-surgery suggests that there is an important role for the combination of inflammatory status (reflected by CPB1 [40], TLT-2 [41], and vWF [42]), markers of atherosclerosis (reflected by SELP [34] PDGF subunit A [36], GP6 [35], CASP-3 [37]), and hypercoagulability (reflected by CPB1 [40], SELP [34], GP6 [35], and vWF [42]). The gene discussed is GP6; the disease is atherosclerosis.