Although the routine measurement of cardiac biomarkers (Troponin T, NT-proBNP, and C-reactive protein) in patients with suspected myocarditis is frequent in clinical praxis and is thought to be beneficial in terms of diagnosis conformation, currently there are no established myocarditis-specific blood biomarkers that can inform the diagnosis and can determine the presence or absence of active myocardial inflammation. This evidence concerns the gene NPPB and myocarditis.