Specifically, the injection of a short hairpin RNA specific for RNF13 (shRNF13) with an intraperitoneal injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to induce the Parkinson’s disease model demonstrated that the group with the silenced RNF13 showed improved motor coordination when compared to an MPTP model only [73]. Here, RNF13 is linked to Parkinson disease.