CASP3 and adenocarcinoma: Moreover, as is shown in Figure 4C,D, the lncCDH5-3:3 knockout significantly increased the number of adenocarcinoma cells (p < 0.05 for the A549 line, and p < 0.01 for the H1975 line), showing caspase-3/7 activity 48 h post transient transfection, which indicates a decrease in the percentage of viable cells.