DYNC1LI2 and cystinosis: However, in some studies, exogenous expression of the dynein subunit, e.g., DYNC1LI2 (dynein, cytoplasmic 1 light intermediate chain 2)—a key cytoskeletal motor protein involved intracellular transport of cargo, organelle trafficking, mitotic spindle assembly, and positioning—rescues the localization of the chaperone-mediated autophagy (CMA) receptor LAMP2A, CMA activity, and the cellular homeostasis in cystinosis-affected PT cells [97].