Of note, similar gene sets were observed aberrantly methylated and expressed in TET2-mutated AML patients, including genes coding for tumor suppressors (PDZD2); transcription modulators (ZNF667, ZNF582, PIAS2, CDK8); nuclear import receptors (TNPO3, IPO8); and myeloid cytokines (CSDA) [103]. This evidence concerns the gene TET2 and acute myeloid leukemia.