However, these mutations are also commonly observed in other blood malignancies, including B and T lymphomas [105,106,107,108,109], such as the angioimmunoblastic T-cell lymphoma (AITL), showing the highest incidence of TET2 mutations (roughly 80%) among all blood cancer types (Table 1). The gene discussed is TET2; the disease is hematopoietic and lymphoid system neoplasm.