Other identified alterations included phosphatase and tensin homolog (PTEN) loss, CHEK2 and BRCA2 (DNA-damage repair [DDR] genes) mutations, CDKN2A, RB1 and CCND1 (cell cycle genes) mutations, along with other PCa-related alterations such as MYC amplification in four cases. Here, MYC is linked to posterior cortical atrophy.