MYC and posterior cortical atrophy: In an in silico study, Böttcher et al. [107] showed that the percentage of genome alterations in PCas from men included in The Cancer Genome Atlas Project (TCGA) and in the Canadian Prostate Cancer Genome Network (CPC-GENE) was three-fold higher in men with IDC-P/CC, and included deletions and amplifications in regions previously associated with aggressive PCa, such as 8p deletions (NKX3.1), 10q23 deletions (PTEN) and 8q amplifications (MYC).