KLK3 and cancer: The other significant prognostic covariates using univariate analyses with a p < 0.2 were age at diagnosis (p = 0.12), cancer stage (p = 0.13), baseline PSA velocity (p = 0.18) for PSA-PFS, and age at diagnosis (p = 0.052), primary therapy type (p = 0.1) and positive node (p = 0.198) for OS.