High GPR64 expression was observed in 90.9% (10/11) of Ewing sarcoma, 36.3% (4/11) of chondrosarcoma, 30.7% (4/13) of osteosarcoma, 80.0% (12/15) of chordoma, 50% (2/4) of fibrosarcoma (FS), 16.6% (2/12) of myxofibrosarcoma (MFS), 11.1% (1/9) of leiomyosarcoma (LMS), 15.4% (2/13) of dedifferentiated liposarcoma, 100% (1/1) of pleomorphic liposarcoma, 0% (0/3) of malignant peripheral nerve sheath tumor (MPNST), 0% (0/3) of myxoid liposarcoma (MLPS), 0% (0/13) of undifferentiated pleomorphic sarcoma (UPS), and 0% (0/4) of synovial sarcoma tissues (Table 2). The gene discussed is ADGRG2; the disease is malignant peripheral nerve sheath tumor.