We then examined STAT1 expression following treatment with increasing MOIs of M002 (0, 0.1, 1 PFU/cell) at 72 h on three separate immunoblots (due to the intensity of STAT1 expression at baseline in the COA129) and found that in the COA3 and COA6 PDX cells, STAT1 decreased with M002 infection (Figure 3C, Figure S1), but in COA129 cells, STAT1 expression increased (Figure 3C, Figure S1). This evidence concerns the gene STAT1 and infection.