On the contrary, it has been shown in another study that when pancreatic tumor cells derived from KC mice are orthotopically implanted in the pancreas, host global Cxcr2 loss inhibits micro-vessel density in pancreatic tumors, but does not inhibit pancreatic cancer growth, and enhances liver metastasis [49]. The gene discussed is CXCR2; the disease is pancreatic neoplasm.