Via a proteomic analysis, 912 proteins were identified in MVs from pleural effusion samples of three NSCLC patients, including several tumor-associated proteins such as EGFR, KRAS, BSG/EMMPRIN/CD147, CEACAM6, CLDN1, CLDN3, and RAB family proteins (e.g., Rab1, Rab3, Rab5, Rab6, Rab11, and Rab13) [118]. This evidence concerns the gene CEACAM6 and non-small cell lung carcinoma.