When compared to exosomes from tumor cells without heat stress (TEX), heat-stressed tumor cell-derived exosomes (HS-TEX) had more chemokines (CCL2, CCL3, CCL4, CCL5, and CCL20), HSPs (HSP60, HSC70, HSP70, and HSP90), and adhesion molecules (e.g., CD54 and CD86). Here, HSP90AA1 is linked to neoplasm.