MAGEC3 and ovarian cancer: We previously reported the linkage between early-onset, BRCA negative ovarian cancers and a locus on Xq27.2 that contains the gene MAGEC3 [1] identified from inheritance patterns in the Familial Ovarian Cancer Registry (Buffalo, NY, USA) [2] that heavily favored clustering among sisters likely due to a father who transmits the risk allele [3].