BCR and acute lymphoblastic leukemia: However, it should be noted that several discrepancies with BL, including MYC translocations being generated in premature B cells via V(D)J recombination, the frequent lack of functional BCR, and the mutation and DNA methylation patterns closely resembling preB lymphoblastic leukemia/lymphoma (pB-ALL/LBL), call into question the classification of preBLL among BL subtypes [82].