FERMT2 and neoplasm: When assessing the effect of loss of Kindlin-2 in mammary glands on tumor growth of E0771 cells, a significant (p < 0.001) reduction in tumor growth (Figure 5D, compare black graph to blue graph) was found when parental E0771 (E-Ctl) cells were injected in the mammary fat pads of K2-deficient (K2--B6) mice as compared to wild-type (WT B6) mice injected with the control E0771 cells.