MMP9 and breast cancer: Oncuria© is a multiplex immunoassay that detects the biomarkers A1AT, APOE, ANG, CA9, IL8, MMP9, MMP10, PAI1, SDC1, and VEGFA, and also showed promising results in 46 de novo BC patients compared with non-cancer controls, with a reported SE and SP of 0.93 each and PPV and NPV of 65% and 99%, respectively [14].