KDR and glioblastoma: The most disrupted kinases in GBM include receptor tyrosine kinases (RTK) such as epidermal growth factor (EGFR), platelet-derived growth factor (PDGFR), hepatocyte growth factor (MET), fibroblast growth factor (FGFR), vascular endothelial growth factor (VEGFR), and insulin-like growth factor 1 receptor (IGF1R).